Publications

  • Deng Z, Law CS, Ho FO, Wang KM, Jones KD, Shin JS, and Shum AK. A defect in thymic tolerance causes T cell-mediated autoimmunity in a murine model of COPA syndrome. J. Immunol, 204: 2360, 2020 (link)
  • Shin JS. Unexpected role of dendritic cells in pulmonary fibrosis. Thorax,74:925, 2019 (link)

  • Borges TJ, Murakami N, Machado FD, Murshid A, Lang BJ, Lopes RL, Bellan LM, Uehara M, Antunes KH, Pérez-Saéz MJ, Birrane G, Vianna P, Gonçalves JIB, Zanin RF, Azzi J, Abdi R, Ishido S, Shin JS, Souza APD, Calderwood SK, Riella LV, Bonorino C. MARCH1-dependent modulation of donor MHC II on CD103+ dendritic cell mitigates alloimmunity. Nat Commun, 9: 3482, 2018 (link)

  • Oh. J, Perry, JSA, Pua, H, Irgens-Moller, N, Ishido, S, Hsieh, CS, and Shin, JS. MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells. J. Cell Biol, Jan 25, 2018 (link)

  • Oh, J, Wu, N, Barczak, AJ, Barbeau, R, Erle, DJ, and Shin, JS. CD40 mediates maturation of thymic dendritic cells driven by self-reactive CD4+ thymocytes and supports development of natural regulatory T cells. J. Immunol, Jan 10, 2018 (link)

  • Bannard, O, McGowan, SJ, Ersching, J, Ishido, S, Victora, GD, Shin, JS, Cyster, JG. Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses. J Exp Med, 213:993, 2016 (link)

  • Oh, J, Shin, JS. The role of dendritic cells in central tolerance. Immune Network, 15:11, 2015 (link)

  • Oh, J, Shin, JS. Molecular mechanism and cellulr function of MHCII ubiquitination. Immunol Rev, 266:134, 2015 (link)

  • Shin, JS, Greer, AM. The role of FceRI expressed in dendritic cells and monocytes. Cell Mol Life Sci, 72:2349, 2015 (link)

  • Greer, AM, Matthay, MA, Kukreja, J, Bhakta, NR, Nguyen, CP, Wolters, PJ, Woodruff, PG, Fahy, JV, Shin, JS. Accumulation of BDCA1+ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS ONE, June 10, 2014 (link)

  • Eggel, A, Baravalle, G, Hobi,G, Kim, B, Buschor, P, Forrer, P, Shin, JS, Vogel, M, Stadler, BM, Dahinden, CA, and Jardetzky, TS. Accelerated dissociation of IgE:FceRI complexes by disruptive inhibitors actively desensitzes allergic effector cells, J of Allergy and Clinical Immunol, 133:1709, 2014 (link)

  • Baravalle, G, Greer, A, LaFlam, T, Shin, JS. Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model. J. Immunol, 192:3280, 2014 (link)

  • Greer, A, Wu, N, Putnam, A, Woodruff, P, Wolters, P, Kinet, JP, Shin, JS. Serum IgE clearance is facilitated by human FceRI internalization. J Clin Invest, 124:1187, 2014 (link)

  • Oh, J, Wu, N, Baravalle, G, Cohn, B, Ma, J, Lo, B, Mellman, I, Ishido, S, Anderson, M, Shin, JS. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med, 210:1069, 2013,  (link)

  • Ma, JK,  Platt MY, Eastham-Anderson, J, Shin, JS*, and Mellman, I*. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length, PNAS. 109:8820, 2012  (link) * Shin, JS. and Mellman, I. contributed equally to this work.

  • Baravalle, G, Park, H, McSweeney, M, Ohmura-Hoshino, M, Matsuki, Y, Ishido, S, Shin, JS. Ubiquitination of CD86 is a Key Mechanism in Regulating Antigen Presentation by Dendritic Cells. J Immunol.  187:2966, 2011. (link)

  • Bloom, O, Unternaehrer, JJ, Jiang, A, Shin, JS, Delamarre, L, Allen, P, and Mellman, I. Spinophilin participates in information transfer at immunological synapses, J Cell Biol. 181:203-11, 2008 (link)

  • Shin, JS, Ebersold, M, Pypaert, M, Delamarre, L, Hartley, A, and Mellman, I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination, Nature. 444:115-8, 2006 (link)

  • Shin, JS, Shelburne, CP, Jin, C, LeFurgey, EA, Abraham, SN. Harboring of particulat allergens within secretory compartments by mast cells following IgE/FcεRI-lipid raft mediated phagocytosis, J Immunol. 177:5791-5800, 2006 (link)

  • Duncan, MJ, Lee, G, Shin, JS. Abraham SN. Bacterial penetration of bladder epithelium through lipid rafts, J Biol Chem. 279: 18944-51, 2004

  • Duncan MJ, Shin JS, Abraham SN. Microbial entry through caveolae: variations on a theme. Cell Microbiol. 4: 783-91, 2002

  • Shin, JS, Abraham, SN. Glycosylphosphatidylinositol-anchored receptor-mediated bacterial endocy-tosis, FEMS Microbiol Lett.197:131-8, 2001.

  • Abraham S, Shin JS, Malaviya R. Type 1 fimbriated Escherichia coli-mast cell interactions in cysti-tis. J Infect Dis.183 Suppl 1:S51-5, 2001 

  • Shin JS, Abraham SN. Co-option of endocytic functions of cellular caveolae by pathogens. Immunology, 102:2-7, 2001

  • Shin JS, Abraham SN. Caveolae as portals of entry for microbes. Microbes Infect. 3:755-61, 2001

  • Shin JS, Abraham SN. Cell biology. Caveolae--not just craters in the cellular landscape. Science. 293:1447-8, 2001. 

  • Shin, JS, Gao, Z, Abraham, SN. Involvement of cellular caveolae in bacterial entry into mast cells, Science. 289:785-8, 2000.

  • Shin JS, Gao Z, Abraham SN. Bacteria-host cell interaction mediated by cellular choles-terol/glycolipid-enriched microdomains. Biosci Rep.19:421-32,1999.