Publications

2018

Oh. J, Perry, JSA, Pua, H, Irgens-Moller, N, Ishido, S, Hsieh, CS, and Shin, JS. MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells. J. Cell Biol, Jan 25, 2018 (link)

Oh, J, Wu, N, Barczak, AJ, Barbeau, R, Erle, DJ, and Shin, JS. CD40 mediates maturation of thymic dendritic cells driven by self-reactive CD4+ thymocytes and supports development of natural regulatory T cells. J. Immunol, Jan 10, 2018 (link)

2016

- Bannard, O, McGowan, SJ, Ersching, J, Ishido, S, Victora, GD, Shin, JS, Cyster, JG. Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses. J Exp Med, 213:993, 2016 (link)

2015

- Oh, J, Shin, JS. The role of dendritic cells in central tolerance. Immune Network, 15:11, 2015 (link)

- Oh, J, Shin, JS. Molecular mechanism and cellulr function of MHCII ubiquitination. Immunol Rev, 266:134, 2015 (link)

- Shin, JS, Greer, AM. The role of FceRI expressed in dendritic cells and monocytes. Cell Mol Life Sci, 72:2349, 2015 (link)

2014

- Greer, AM, Matthay, MA, Kukreja, J, Bhakta, NR, Nguyen, CP, Wolters, PJ, Woodruff, PG, Fahy, JV, Shin, JS. Accumulation of BDCA1+ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS ONE, June 10, 2014 (link)

- Eggel, A, Baravalle, G, Hobi,G, Kim, B, Buschor, P, Forrer, P, Shin, JS, Vogel, M, Stadler, BM, Dahinden, CA, and Jardetzky, TS. Accelerated dissociation of IgE:FceRI complexes by disruptive inhibitors actively desensitzes allergic effector cells, J of Allergy and Clinical Immunol, 133:1709, 2014 (link)

- Baravalle, G, Greer, A, LaFlam, T, Shin, JS. Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model. J. Immunol, 192:3280, 2014 (link)

- Greer, A, Wu, N, Putnam, A, Woodruff, P, Wolters, P, Kinet, JP, Shin, JS. Serum IgE clearance is facilitated by human FceRI internalization. J Clin Invest, 124:1187, 2014 (link)

2013

- Oh, J, Wu, N, Baravalle, G, Cohn, B, Ma, J, Lo, B, Mellman, I, Ishido, S, Anderson, M, Shin, JS. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med, 210:1069, 2013,  (link

  * Oh, J. and Wu, N. contributed equally to this work.

  * Highlighted in Nature Reviews Immunology 13:472, 2013 (link)

  * Selected for F1000Prime. (link)

2012 

- Ma, JK,  Platt MY, Eastham-Anderson, J, Shin, JS*, and Mellman, I*. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length, PNAS. 109:8820, 2012  (link)

  * Shin, JS. and Mellman, I. contributed equally to this work.

2011

- Baravalle, G, Park, H, McSweeney, M, Ohmura-Hoshino, M, Matsuki, Y, Ishido, S, Shin, JS. Ubiquitination of CD86 is a Key Mechanism in Regulating Antigen Presentation by Dendritic Cells. J Immunol.  187:2966, 2011. (link)

2008 and before

- Bloom, O, Unternaehrer, JJ, Jiang, A, Shin, JS, Delamarre, L, Allen, P, and Mellman, I. Spinophilin participates in information transfer at immunological synapses, J Cell Biol. 181:203-11, 2008 (link)

   * Commented in JCB 181:181, 2008 (link)

 - Shin, JS, Ebersold, M, Pypaert, M, Delamarre, L, Hartley, A, and Mellman, I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination, Nature. 444:115-8, 2006 (link)

   * Selected for F1000Prime (link)

 - Shin, JS, Shelburne, CP, Jin, C, LeFurgey, EA, Abraham, SN. Harboring of particulat allergens within secretory compartments by mast cells following IgE/FcεRI-lipid raft mediated phagocytosis, J Immunol. 177:5791-5800, 2006 (link)

 - Duncan, MJ, Lee, G, Shin, JS. Abraham SN. Bacterial penetration of bladder epithelium through lipid rafts, J Biol Chem. 279: 18944-51, 2004

 - Duncan MJ, Shin JS, Abraham SN. Microbial entry through caveolae: variations on a theme. Cell Microbiol. 4: 783-91, 2002

 - Shin, JS, Abraham, SN. Glycosylphosphatidylinositol-anchored receptor-mediated bacterial endocy-tosis, FEMS Microbiol Lett.197:131-8, 2001.

 - Abraham S, Shin JS, Malaviya R. Type 1 fimbriated Escherichia coli-mast cell interactions in cysti-tis. J Infect Dis.183 Suppl 1:S51-5, 2001 

 - Shin JS, Abraham SN. Co-option of endocytic functions of cellular caveolae by pathogens. Immunology, 102:2-7, 2001

 - Shin JS, Abraham SN. Caveolae as portals of entry for microbes. Microbes Infect. 3:755-61, 2001

 - Shin JS, Abraham SN. Cell biology. Caveolae--not just craters in the cellular landscape. Science. 293:1447-8, 2001. 

 - Shin, JS, Gao, Z, Abraham, SN. Involvement of cellular caveolae in bacterial entry into mast cells, Science. 289:785-8, 2000.

  * Commented in Science 289:732, 2000

  * Selected for F1000Prime

 - Shin JS, Gao Z, Abraham SN. Bacteria-host cell interaction mediated by cellular choles-terol/glycolipid-enriched microdomains. Biosci Rep.19:421-32,1999.